Alzheimer�s disease (AD) is characterized by progressive cognitive decline usually beginning with impairment in the ability to form\nrecent memories.Nonavailability of definitive therapeutic strategy urges developing pharmacological targets based on cell signaling\npathways. A great revival of interest in nutraceuticals and adjuvant therapy has been put forward. Tea polyphenols for the ir multiple\nhealth benefits have also attracted the attention of researchers. Tea catechins showed enough potentiality to be used in future as\ntherapeutic targets to provide neuroprotection against AD. This review attempts to present a concise map of different receptor\nsignaling pathways associated with AD with an insight into drug designing based on the proposed signaling pathways, molecular\nmechanistic details of AD pathogenesis, and a scientific rationale for using tea polyphenols as proposed therapeutic agents in AD.
Loading....